Company

Alexion Pharma GmbH

21 orphan drug statuses6 medicines14 rare diseases

Alexion Pharma GmbH holds 21 Swissmedic orphan drug statuses in Switzerland, covering 14 rare diseases.

6 of its medicines are published with an authorisation number. Placing a medicine on the Swiss market requires an authorisation holder domiciled in Switzerland; the orphan drug status application does not, where a Swiss postal address suffices.

Medicines

Orphan designations

Swissmedic publishes one row per medicine and orphan indication: the indication in the wording of the decision, the date the status was granted and, where the status was withdrawn, the withdrawal date. The table below reproduces those rows unchanged and links every indication to the matching rare disease in the directory.

One row per orphan indication, exactly as Swissmedic publishes it.
Orphan indicationDiseaseStatus grantedStatus withdrawn
Behandlung der primären IgA NephropathiePrimary IgA nephropathy25/08/2026Status active
Behandlung von HypophosphatasieHypophosphatasia04/09/2025Status active
Behandlung der thrombotischen Mikroangiopathie nach hämatopoetischer Stammzelltransplantation (HSCT-TMA)Conditioning before stem cell transplantation03/09/2025Status active
Behandlung von Myasthenia Gravis (MG)Myasthenia gravis26/08/2025Status active
Behandlung von ATTR AmyloidoseTransthyretin amyloidosis (ATTR)15/04/2025Status active
Behandlung der paroxysmalen nächtlichen HämoglobinurieParoxysmal nocturnal haemoglobinuria (PNH)01/06/2023Status active
Behandlung von Neuromyelitis-optica-Spektrum-Erkrankungen (NMOSD)Neuromyelitis optica spectrum disorder (NMOSD)27/02/2023Status active
Behandlung von Myasthenia Gravis (MG)Myasthenia gravis22/06/2022Status active
Behandlung von Morbus WilsonWilson disease14/01/2022Status active
Behandlung von AL AmyloidoseAL amyloidosis (light-chain amyloidosis)11/01/2022Status active
Behandlung des atypischen hämolytisch-urämischen Syndroms (aHUS)Atypical haemolytic uraemic syndrome (aHUS)13/07/2020Status active
Traitement de l'Hémoglobinurie paroxystique nocturneParoxysmal nocturnal haemoglobinuria (PNH)19/09/2019Status active
Behandlung von Erkrankungen des Neuromyelitis-Optica-SpektrumsNeuromyelitis optica spectrum disorder (NMOSD)13/09/2019Status active
Behandlung von Neurofibromatose Typ 1 (NF1)Neurofibromatosis type 1 (NF1)08/03/2019Status active
Prévention du rejet de greffe aiguë suite à la transplantation d'organes solidesTransplant rejection after solid organ transplantation09/03/2017Status active
Myasthenia GravisMyasthenia gravis02/12/2016Status active
Behandlung der Mukopolysaccharidose Typ IIIB (Sanfilippo-B-Syndrom)Mucopolysaccharidoses (MPS)29/03/2016Status active
Behandlung der HypophosphatasieHypophosphatasia25/02/2013Status active
Wolman-Krankheit oder Cholesterinester-Speicherkrankheit (auf intrazellulärem Lipase-Mangel basierte Speicherkrankheit)Wolman disease and cholesteryl ester storage disease02/07/2012Status active
Atypisches hämolytisch-urämisches SyndromAtypical haemolytic uraemic syndrome (aHUS)25/11/2011Status active
Behandlung der paroxysmalen nächtlichen HämoglobinurieParoxysmal nocturnal haemoglobinuria (PNH)03/08/2007Status active

Reimbursement

Whether this company's medicines are paid for by compulsory health insurance depends on the FOPH specialities list (SL), not on the orphan drug status. Medicines that are not listed can be reimbursed case by case under Art. 71a-71d KVV.

Search the specialities list

Frequently asked questions

How does a medicine obtain orphan drug status in Switzerland?

On application to Swissmedic. It requires a life-threatening or chronically debilitating disease affecting no more than 5 in 10,000 people in Switzerland, or an existing recognition in a country with comparable medicinal product control (Art. 4 para. 1 let. a decies TPA, Art. 4 TPLO).

What does the status actually give you?

The simplified authorisation procedure (Art. 14 para. 1 let. f TPA), priority assessment, a waiver of the flat-rate fee for the new authorisation application and, on request, 15 years of document protection (Art. 11b para. 4 TPA). There is no market exclusivity as in the EU.

How current is the data on Alexion Pharma GmbH?

Swissmedic publishes the list of medicinal products with orphan drug status under Art. 7 TPLO and updates it monthly. The date of the data set processed here is shown at the foot of every page.

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You can enquire about orphan drug status, authorisation and reimbursement in Switzerland. Any specialist service and its scope are agreed separately with the external partner.

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